12bo 解:作BO⊥AC于O;∵是直二面角B-AC-D∴BO⊥平面ADC;在△ABC,AB=4,BC=3?AC=5;∵12BO?AC=12AB?BC?BO=125.∴VB-ACD=13?BO?S△ADC=13×125×12×3×4=245.故答案为:245.